Kazushige Yokoyama
Professor
ISC 326F
(585)245-5320
yokoyama@geneseo.edu
Dr. Yokoyama has been a member of the 91影视 faculty since 2001.

Office Hours

Curriculum Vitae
Education
B.S. & M.S. University of Kobe, Japan (with Professor Hajime Kato)
Ph.D. University of Colorado (with Professor Carl Lineberger)
Post-Doctoral Fellow at University of Minnesota (with Professor Paul Barbara)
Publications: Papers
K. Yokoyama, E. Barbour, R. Hirschkind, Bryan Martinez Hernandez, K. Hausrath, and Theresa Lam
淧rotein Corona Formation and Aggregation Process of Amyloid beta 1-40 Coated Gold Nano-Colloids, Langmuir, Vol. 40, pp. 1728-1746 (2024). https://pubs.acs.org/doi/full/10.1021/acs.langmuir.3c02923
K. Yokoyama, J. Thomas, W. Ardner, M. Kieft, L. Neuwirth, and W. Lieu, 淎n Approach for In Situ Detection of Amyloid Formations within the Hippocampus of the Cohen檚 Alzheimer檚 Disease Rat Model by Surface Enhanced Raman Scattering Methods, Journal of Neuroscience Methods, Vol. 393 pp. 109892 – 109901 (2023)
https://authors.elsevier.com/a/1h9HSbXTP5POR
K. Yokoyama and A. Ichiki, 淎dsorption of Amyloidogenic Peptides at Nano-Scale Interface Studied by Spectroscopic Approach, Journal of Visualized Experiments (under the review).
K. Yokoyama, T. Lam, J. Santariello, and A. Ichiki, 淣ano-size dependent Reversible Self-assembly of SARS-CoV-2 Omicron Spike protein, Colloids and Surfaces A, Volume 647 128967 – 128973 (2022)
https://www.sciencedirect.com/science/article/pii/S0927775722007221?via%3Dihub
K. Yokoyama and A. Ichiki, 淎 Model for Nano-Scale Spherical Surface Coverage and Protein Corona Formation by Amyloidogenic Peptides , The International Journal of Biocomputing and Nano Technology Volume 1, pp. 21 28 (2022)
K. Yokoyama and A. Ichiki
“Nano-size Dependence in the Adsorption by the SARS-CoV-2 Spike Protein over Gold Colloid”
[Colloid and Surfaces A,Volume 615, pp. 126275-126281 (2021)
K. Yokoyama and A. Ichiki, “Nano-Size Dependence in the Adsorption by the SARS-CoV-2 Spike Protein over Gold Colloid”, Colloids and Surfaces A, Vol. 40 pp. 100356-100362 (2021)
K. Yokoyama and A. Ichiki, 淲hat can peptide-coated nanoparticles tell us about the causes of dementia?, Research OutreachJournal of Visualized Experiments, pp. 110-113, Issue 116 (2020)
http://cdn.researchoutreach.org/Flipbooks/RO116/index.html#
K. Yokoyama, K. Brown, P. Shevlin, J. Jenkins, E. D’Ambrosio, N. Ralbovsky, J. Battaglia, I. Deshmukh, and A. Ichiki, 淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particles Surfaces, Int. J. Mol. Sci., Vol 20, pp. 5354-5380 (2019). https://www.mdpi.com/1422-0067/20/21/5354
K. Yokoyama, H. Chen, A. Islam, I. Deshmukh, P. Shevlin, K. Brown, and A. Ichiki, “Dynamical Investigation of Adsorption Orientation of Amyloid Beta Peptide 1-40 at Nano-Scale Gold Surface, BAOJ Chemistry, Vol. 5 (1), pp. 1-20 (2019).
Publications: Text Book & Book Chapters
[TEXT BOOKS]
K. Yokoyama 淢odern Physical Chemistry for Bioscience Students – Friendly and Short Cut Guide for Physical Chemistry (2011) Linus Publication, ISBN# 1-60797-185-2 First Edition (604 pages), ISBN# 1-60797-246-8 Second Edition.(618 pages), ISBN# 1-60797-337-5 Third Edition.(592 pages), ISBN978-1-60797-897-8 (2020)
K. Yokoyama (Editor) 淔rontiers in Nanoscience for Biomedical Research Research Signpost, ISBN# 978-81-308-0537-5, (2014).
[Book Chapters]
K. Yokoyama, 淚nvestigation of protein-protein interaction utilizing nano-gold colloid surface plasmon resonance: Application to SARS CoV-2 spike protein coated gold colloids, ACS Symposium Series Volume 1428, Physical Chemistry Research at Undergraduate Institutions Innovative and impactful approaches Volume 2, Chapter 9 pp. 145-164, (2023) Edited by Todd Hopkins and Carol Parish, ISBN 978-0-8412-9743-2.
Kazushige Yokoyama, Kieran Brown, Peter Shevlin, Jack Jenkins, Elizabeth D橝mbrosio, Nicole Ralbovsky, Jessica Battaglia, Ishan Deshmukh and Akane Ichiki, 淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particle Surfaces pp. 75-102 in Designer Biopolymers Self-Assembling Proteins and Nucleic Acids Edited by Ayae Sugawara-Narutaki Yukiko Kamiya MDPI, Basel, Switzerland (2020)
ISBN 978-3-03936-370-4
K. Yokoyama and A. Ichiki 淐hapter 3: Oligomerization and Adsorption Orientation of Amyloidogenic Peptides over Nano-Gold Colloidal Particle Surfaces pp. 139-194 in Advances in Chemical Research, Ed. by James C. Taylor, Nova Science Publishing, Hauppauge, NY, USA. (2020) ISBN: 978-1-53617-627-8.
K. Yokoyama, K. Brown, P. Shevlin, J. Jenkins, E. D橝mbrosio, N. Ralbovsky, J. Battaglia, I. Deshmukh and Akane Ichiki, 淓xamination of Adsorption Orientation of Amyloidogenic Peptides Over Nano-Gold Colloidal Particle Surfaces, e-Book Book Chapter, Prime Archives in Molecular Biology, VideLeaf.
Kazushige Yokoyama 淐ontrolling Reversible Self Assembly Path of Amyloid Beta Peptide over Gold Colloidal nanoparticle檚 Surface Book Chapter in 淣anoscale Spectroscopy with Applications Sarhan M. Musa 揈d (CRC Press-Taylor and Francis Group, LLC) ISBN# 9781466568532 (2013) [http://www.crcpress.com/product/isbn/9781466568532]
Kazushige Yokoyama 淣ano Size Dependent Properties of Colloidal Surfaces Book Chapter in 淐olloids: Classification, Properties and Applications (Nova Science Publishing) (2012)
Media Related
ACS Chemical Engineering News Pictures in Chemistry (November, 2022)
White light image of Amyloid beta 12-28 coated Gold colloid aggregates
(https://cen.acs.org/biological-chemistry/Chemistry-Pictures-Van-Goghs-Worrisome/100/web/2022/11?utm_source=Newsletter&utm_medium=Newsletter&utm_campaign=CEN)
Science Animation
YouTube “How do fibrils form?”
Yokovid Project “91影视 Community Outreach through Science of COVID-19”
YouTube
Pod-Cast “Dimentia, degeneration, and gold nanoparticles”
https://researchpod.org/health-medicine/dementia-degeneration-and-gold-nanoparticles
Research Outreach (Science Magazine)
Kazushige Yokoyama & Akane Ichiki
“What can peptide-coated nanoparticles tell us about the causes of dementia?”
Issue 116 (pp. 110-113)
https://researchoutreach.org/publications/issue-116/
COVID Information Commons (CIC) Webinar: Winter 2024 Research Lightning Talks and Q & A
https://covidinfocommons.datascience.columbia.edu/content/kazushige-yokoyama-suny-geneseo
K. Yokoyama 滻nvestigating Reversible Aggregation of SARS-CoV-2 Spike Protein-Coated Gold Colloid
Research Group Members
From the left:
Christopher Kolilias (’26, Chemistry), VictoriaBrzezinski (’25, Biology), Nathan Bobowski (’28, Chemistry), Mitsuki Tabei (’26, Biophysics), , Nicole Mathewson (’26, Biology).
91影视 COVID19 Study Group (Team Yokovid)
Textbooks/Media
K. Yokoyama (Editor) 淔rontiers in Nanoscience for Biomedical Research Research Signpost, ISBN# 978-81-308-0537-5, (2014)

K. Yokoyama
Friendly and Short Cut Guide for Physical Chemistry
Modern Physical Chemistry for Bioscience Students
(4th edition) Linus Learning ISBN978-1-60797-897-8 (2020)
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笔谤辞产濒别尘蝉别迟听
Modern Physical Chemistry for Bioscience Students
Linus Learning (2021) ISBN 978-1-60797-931-9
Media (YouTube/iPod)
- Science behind COVID-19 (Community Outreach Project)
Brochure & You Tube - Podcast: ResearchPod 淒ementia, degeneration, and gold nanoparticles (2019)
- Video Abstract 淣anoparticles and dementia: understanding the role of fibrils (2019)
- Research Outreach 淲hat can peptide-coated nanoparticles tell us about? Issue No. 116, pp. 110-113 (2020). (Research Outreach Featured Article page: )
- Science Animation 淗ow do fibrils form? (2020)
- Yokoyama, K., Thomas, J., Ardner, W., Neuwirth, L.S. & Liu, W. Method for in situ detection of amyloid formation in the hippocampus of the Cohen’s Alzheimer’s disease rat model by Surface Enhanced Raman Scattering. inSSRN听(, 2022).